IR: 5 mg/7.5 mg/10 mg/12.5 mg/15 mg/20 mg/30 mgįunctions by increasing levels and inhibiting reuptake of stimulatory neurotransmitters such as dopamine and norepinephrine.Īcts as a TAAR1 agonist and VMAT2 inhibitor.Īppetite loss. IR (Immediate release) or XR (Extended release) Mixed Amphetamine Salts (~75% Dextroamphetamine & ~25% Levoamphetamine) Adderall is comprised of 3/4 dextroamphetamine and 1/4 levoamphetamine (the left-handed stereoisomer). Dexedrine is comprised fully of dextroamphetamine, the right-handed (dextrorotatory) stereoisomer of amphetamine. Adderall Comparison ChartĪs you can determine from the chart below, Dexedrine and Adderall are relatively similar drugs. Dextroamphetamine elicits nearly three-fold more CNS stimulation than levoamphetamine. However, Dexedrine can be considered to be a more potent stimulant than Adderall due to the fact that it contains 100% dextroamphetamine whereas Adderall only contains 75%. Adderall differed from Dexedrine in that its formulation was 75% dextroamphetamine and 25% levoamphetamine or a mixture of amphetamine salts.Īdderall and Dexedrine are considered similar drugs due to the fact that they are both comprised of amphetamine stereoisomers. Years later (1996), the FDA approved a drug comprised of mixed amphetamine salts called Adderall. Dextroamphetamine is considered a popular military stimulant, and has been utilized throughout history such as in World War II to offset fatigue and to help troops stay up for nighttime missions.Īmedra Pharmaceuticals began marketing Dexedrine for the treatment of attention-deficit/hyperactivity disorder in 1982 as a potent stimulant for those who didn’t respond well to methylphenidate. The active ingredient in Dexedrine is “dextroamphetamine” which is regarded as the “right-handed” stereoisomer of the molecule amphetamine. Dexedrine is a psychostimulant drug primarily used to treat severe cases of ADHD and narcolepsy.
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